Three-lobed bur-marigold has long been used to treat skin conditions in both adults and children. In Russian folk tradition, the plant is known by many names, including scrofula herb, beggar-ticks, marsh arrow, two-tooth herb, dog bur, and others. The plant was extremely popular in Russia, where it was harvested across 29 provinces.
Infusions made from the herb are traditionally used internally to support the body during colds, and externally to treat exudative diathesis, pyoderma, atopic dermatitis, and eczema of various origins. A Russian herbal medical guide from 1893 states that the plant was believed to help relieve coughs and thin thick mucus. Fresh green herb was also traditionally applied to wounds from venomous snake bites to promote healing. Additionally, the leaves and flowers were historically used to produce bright yellow, cream, and brown dyes for silk and wool fabrics.